Jayanthi, S., Koppolu, B., Nguyen, K.G., Smith, S.G., Felber, B.K., Kumar, T.K.S., Zaharoff, D.A. Modulation of Interleukin-12 activity in the presence of heparin. Scientific Reports, 7: 5360, 2017. Download

Smith, S.G. Baltz, J.L., Koppolu, B., Ravindranathan, S., Nguyen, K. Zaharoff, D.A. Immunological mechanisms of intravesical chitosan/interleukin-12 immunotherapy against murine bladder cancer. OncoImmunology, 5(12): e1259050, 2016. Download

Smith, S.G., Zaharoff, D.A. Future Directions in Bladder Cancer Immunotherapy: Towards Adaptive Immunity. Immunotherapy, 8(3):351-65, 2016. Download

Ravindranathan, S., Koppolu, B., Smith, S.G., Zaharoff, D.A. Effect of chitosan properties on immunoreactivity. Marine Drugs, 14(5): 91, 2016. Download

Smith, S.G., Koppolu, B., Ravindranathan, S., Kurtz, S.L., Yang, L., Katz, M.D., Zaharoff, D.A. Intravesical Chitosan/IL-12 Immunotherapy Induces Tumor-Specific Systemic Immunity against Bladder Cancer. Cancer Immunology Immunotherapy, 64(6):689-96, 2015. Download

Vo, J. L., Yang, L., Kurtz, S. L., Smith, S. G., Koppolu, B., Ravindranathan, S., & Zaharoff, D. A. Neoadjuvant immunotherapy with chitosan and interleukin-12 to control breast cancer metastasis. OncoImmunology, 3(12): e968001, 2014. Download

Kurtz, S. L., Ravindranathan, S., & Zaharoff, D. A. Current status of autologous breast tumor cell-based vaccines. Expert review of vaccines, 13(12), 1439-1445, 2014. Download

Jayanthi, S., Koppolu, B., Smith, S. G., Jalah, R., Bear, J., Rosati, M., Pavakis, G.N., Felber, B.K., Zaharoff, D. A. & Kumar, T. K. S. Efficient production and purification of recombinant human interleukin-12 (IL-12) overexpressed in mammalian cells without affinity tag. Protein expression and purification, 102, 76-84, 2014. Download

Koppolu, B., Smith, S. G., Ravindranathan, S., Jayanthi, S., Kumar, T. K. S., & Zaharoff, D. A. Controlling chitosan-based encapsulation for protein and vaccine delivery. Biomaterials, 35(14), 4382-4389, 2014. Download

Kim, J.-W., Galanzha, E.I., Zaharoff, D.A., Griffin, R.J., Zharov, V.I. Nanotheranostics of Circulating Tumor Cells and Other Pathological Cells In Vivo. Molecular Pharmaceutics, 10(3):813-30, 2013. Download

Yang, L., Zaharoff, D.A. Role of chitosan co-formulation in enhancing interleukin-12 delivery and antitumor activity. Biomaterials, 34:3828-36, 2013. Download

Koppolu, B., Zaharoff, D.A. The effect of antigen encapsulation in chitosan particles on uptake, activation and presentation by antigen presenting cells. Biomaterials, 34:2359-69, 2013. Download

Heffernan, M. J., Zaharoff, D. A., Fallon, J. K., Schlom, J., & Greiner, J. W. In vivo efficacy of a chitosan/IL-12 adjuvant system for protein-based vaccines. Biomaterials, 32(3), 926-932, 2011. Download

Zaharoff, D.A., Hance, K.W., Rogers, C.J., Schlom, J., Greiner, J.W. Intratumoral immunotherapy of established solid tumors with chitosan/IL-12. Journal of Immunotherapy, 33(7):697-705, 2010. Download

Zaharoff, D.A., Hoffman, B.S., Hooper, H.B., Benjamin, C.J., Khurana, K.K., Hance, K.W., Rogers, C.J., Pinto, P.A., Schlom, J., Greiner, J.W. Intravesical immunotherapy of superficial bladder cancer with chitosan/IL-12. Cancer Research, 69(15):6192-9, 2009. Download

Hance, K.W., Rogers, C.J., Zaharoff, D.A., Canter, D., Schlom, J., Greiner, J.W. The antitumor and immunoadjuvant effects of IFN-alpha in combination with recombinant poxvirus vaccines. Clinical Cancer Research, 15(7):2387-96, 2009. Download

Rogers, C.J., Zaharoff, D.A., Hance, K.W., Perkins, S.N., Hursting, S.D., Schlom, J, Greiner, J.W. Exercise enhances vaccine-induced antigen-specific T cell responses. Vaccine, 26(42): 5407-15, 2008.

Zaharoff, D.A., Henshaw, J.W., Mossop, B.J., Yuan, F. Mechanistic analysis of electroporation-induced cellular uptake of macromolecules. Experimental Biology and Medicine, 233(1):94-105, 2008.

Zeytin, H., Reali, E., Zaharoff, D.A., Rogers, C.J., Schlom, J., Greiner, J.W. NK Cell Recruitment to Regional Lymph Nodes and Priming of Tumor-Specific Host Immunity. Journal of Interferon and Cytokine Research, 28(2):73-87, 2008.

Zaharoff, D.A., Rogers, C.J., Hance, K.W., Schlom, J., Greiner, J.W. Chitosan solution enhances the immunoadjuvant properties of GM-CSF. Vaccine, 25(11):8673-8686, 2007.

Rogers, C. J., Berrigan D., Zaharoff, D.A., Hance, K.W., Patel, A.C., Perkins, S.N., Schlom J., Greiner J.W., and Hursting, S.D. Exercise and calorie restriction differentially alter systemic and mucosal immunity. Journal of Nutrition, 138:115-122, 2008.

Zaharoff, D.A., Rogers, C.J., Hance, K.W., Schlom, J., Greiner, J.W. Chitosan solution enhances both humoral and cell-mediated immune responses to subcutaneous vaccination. Vaccine, 25(11):2085-2094, 2007.

Henshaw, J.W., Zaharoff, D.A., Mossop, B.J., Yuan, F. Electric field-mediated transport of plasmid DNA in tumor interstitium in vivo. Bioelectrochemistry, 71(2):233-42, 2007

Mossop, B.J., Barr, R.C., Henshaw, J.W., Zaharoff, D.A., Yuan, F. Electric fields in tumors exposed to external voltage sources: Implication for electric field - mediated drug and gene delivery. Annals of Biomedical Engineering, 34(7):1564-1572, 2006.

McGuire, S.M., Zaharoff, D.A., Yuan, F. Nonlinear dependence of hydraulic conductivity on tissue deformation during intratumoral infusion. Annals of Biomedical Engineering, 34(7):1173-1181, 2006.

Henshaw, J.W., Zaharoff, D.A., Mossop, B.J., Yuan, F. A single molecule detection method for understanding mechanisms of electric-field mediated interstitial transport of genes. Bioelectrochemistry, 69: 248-253, 2006.

Mossop, B.J., Barr, R.C., Zaharoff, D.A., Yuan, F. Electric fields within cells as a function of membrane resistivity – A model study. IEEE Trans. Nanobioscience, 3(3):225-231, 2004.

Zaharoff, D.A., Yuan, F. Effects of pulse strength and pulse duration on in vitro DNA electromobility. Bioelectrochemistry, 62(1):37-45, 2004.

Zhang, L., Widera, G., Bleecher, S., Zaharoff, D.A., Mossop, B., Rabussay, D. Accelerated immune response to DNA vaccines. DNA and Cell Biology, 22(12):815-822, 2003.

Zaharoff, D.A., Barr, R.C., Li, C.Y., Yuan, F. Electromobility of plasmid DNA in tumor tissues during electric field-mediated gene delivery. Gene Therapy, 9:1286-1290, 2002.

Lohr, F., Lo, D.Y., Zaharoff, D.A., Hu K., Zhang, X., Li, Y., Zhao, Y., Dewhirst, M.W., Yuan, F., Li, C.-Y. Effective tumor therapy with plasmid-encoded cytokines combined with in vivo electroporation. Cancer Research, 61(8):3281-4, 2001.